The purpose of the performed research was to define the possibilities of using donor cryopreserved cell material (mesenchymal stem cells which had been separated from adipose tissue) for protection of the transplanted fat graft from tissue absorption.
The results of the research showed that fortification of fat graft with cryopreserved allogenic mesenchymal multipotent stem cells that had been separated from adipose tissue leads to activation of destructive and inflammatory process in fat graft, deterioration of adipocyte survival and as a result to shortage of transplant weight.
It appears impractical to use donor cryopreserved stem cells in clinical practice with the purpose of protection of the transplanted adipose tissue from tissue absorption.