The parameters obtained in the control group were slightly above the conventional normal range ((2,44±0,19) ng/ml; N = 0,4–2,2 ng/ml). In our opinion, exactly teenage group with increased requirements for growth and development creates conditions for increased production of C-peptide and insulin levels, providing adequate growth and development of adolescents during puberty. In the overweight group of children C-peptide was elevated in 17 (47.2%) children, with a tendency to higher rates of C-peptide in the older age group (in 1.3 times). In obese children C-peptide was increased in 33 (55.0%) cases, which is more than two times higher than in control group. In the group of obese children aged 14–18 years, boys produced significantly higher levels of C-peptide ((3.64±0.55) ng/ml) compared with control group ((2.45±0.39) ng/ml, p<0.05). A similar trend is observed in overweight children aged 10–13 years, where the studied parameter was higher ((2.98±0.69) ng/ml) in boys compared with the girls in the same subgroup ((1.77±0.26) ng/ml, p<0.05), and compared with a group of healthy children ((2.45±0.39) ng/ml).
However, these differences were not statistically significant. Elevated levels of C-peptide indicate the presence of abnormal hormone values already in the overweight group, with more serious disturbances in hormonal levels of C-peptide with development of obesity. The combination of pathological C-peptide levels with overweight requires medical treatment in order to stop the progression of the disease and obesity.