THE STATE OF PROOXIDANT AND ANTIOXIDANT SYSTEMS IN THE BRONCHI OF GUINEA PIGS UNDER CONDITIONS OF PNEUMONIA DEVELOPMENT AND ITS DISTURBANCES CORRECTION WITH CORVITINI

In the present work it was established that under the modeled experimental pneumonia characterized by gradual growth of dien conjugates and malonic dialdehyde content on the 1st, 3rd, 5th and 7th days, compensatory growth of superoxide dismutase, catalase, peroxidase and glutathion reductase activity on the 1st and 3rd days with a subsequent reduction of superoxide dismutase, catalase, peroxidase and glutathion reductase activity on the 5th, 7th days.

Injections of corvitini during 7 days (40 mg/kg intraperitoneally) reduce activity of dien conjugates and malonic dialdehyde and increases superoxide dismutase, catalase, peroxidase and glutathion reductase activity.