With the stomatitis simulation in the rats with the aid of the bee poison applications they caused the development of inflammation in the oral mucosa (raising of the level of the inflammation markers: elastase, MDA) and disbiosis (Levitsky’s enzymatic method).
The rinsing of the oral cavity by the diluted extract, which contains the biologically active materials of grape leaves, significantly reduced the level of inflammatory and dysbiotic processes in the oral mucosa.